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Metabolic basis for changes leading to Alzheimer’s disease identified

Amyloid plaques and tau (or neurofibrillary tangles) are the typical pathological lesions present in the shrinking brains of patients affected by Alzheimer’s disease. These pathological changes can be observed under a microscope, but the severity of the changes varies throughout the brain. A recent study by Xu et al. (Scientific Reports, 9th June 2016) investigated [...]

Metabolic basis for changes leading to Alzheimer’s disease identified2017-04-06T00:20:01+00:00

Link discovered between exercise, healthy mitochondria and a healthy brain

Adequate exercise is essential to maintain not only a healthy body, but also a healthy mind. Physical exercise is beneficial for brain plasticity (the brain’s ability to change throughout life), increasing cognition and reducing the risk of dementia, particularly Alzheimer’s disease. Although we know that physical exercise reduces the risk of Alzheimer’s disease, we still [...]

Link discovered between exercise, healthy mitochondria and a healthy brain2017-04-06T00:20:01+00:00

Marijuana identified as potential treatment for Alzheimer’s disease

Most people who suffer from Alzheimer’s disease are affected by neuropsychiatric symptoms, primarily depression, sleeping issues, apathy and verbal and physical agitation. As the disease progresses, delusions, hallucinations and aggression become more common. These neuropsychiatric symptoms have a major impact on the patient’s (and their caregiver’s) quality of life, and often the disease progresses more [...]

Marijuana identified as potential treatment for Alzheimer’s disease2017-04-06T00:20:01+00:00

How is the Alzheimer’s Disease APOE Gene Inherited?

The APOE gene linked to Late-Onset Alzheimer's disease is present on one of the autosomal chromosomes (chromosome 19). Each of us inherits one of each autosomal chromosome from each parent, and if we have children, we pass one of each autosomal chromosome to the next generation. So this means, if you have two identical copies [...]

How is the Alzheimer’s Disease APOE Gene Inherited?2017-04-06T00:20:01+00:00

The APOE Genetics of Alzheimer’s Disease

There are two general types of Alzheimer’s disease known as Early-Onset Familial Alzheimer’s and Late-Onset Alzheimer’s. Both diseases have similar symptoms and progression, but differ in the age of onset and the genetic cause. Early-Onset Alzheimer’s only occurs in less than 10% of cases and the first symptoms appear before the age of 65. This [...]

The APOE Genetics of Alzheimer’s Disease2017-04-06T00:20:02+00:00

Is Aducanumab the potential Alzheimer’s Disease wonder drug?

One of the major changes observed in the brain of an Alzheimer’s patient is the accumulation of the beta-amyloid protein between the neurons. These toxic amyloid plaques prevent the essential synapses between the neurons and may also activate a damaging inflammatory response. Several groups have been unsuccessfully attempting to use antibodies to selectively target and [...]

Is Aducanumab the potential Alzheimer’s Disease wonder drug?2017-04-06T00:20:02+00:00

Animal studies reveal certain NSAIDs may potentially protect against Alzheimer’s Disease

Non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, are among the most common medications for pain relief, lowering fever and reducing swelling. Most NSAIDs inhibit the cyclooxygenase enzymes COX-1 and COX-2. These enzymes help with the formation of prostaglandins – the ‘pain’ molecules released from damaged tissue. There is increasing evidence that many NSAIDs [...]

Animal studies reveal certain NSAIDs may potentially protect against Alzheimer’s Disease2017-04-06T00:20:02+00:00

What brain changes occur in Alzheimer’s patients?

The human brain has three major components. The main part is the cerebrum surrounded by an outer layer known as the cerebral cortex. This part of the brain is required for remembering, problem solving, feeling and thinking. At the back of the brain is the cerebellum, important for coordination and balance. The brain stem is [...]

What brain changes occur in Alzheimer’s patients?2017-04-06T00:20:02+00:00

How to tell the difference between normal aging and Alzheimer’s?

There are ten early warning signs and symptoms of Alzheimer’s disease. One or more of these symptoms that are severe enough to disrupt daily life might be a sign of Alzheimer’s. The signs and symptoms of Alzheimer’s include loss of memory; difficulty in reasoning; trouble in completing daily routine; impaired awareness about time and location; [...]

How to tell the difference between normal aging and Alzheimer’s?2017-04-06T00:20:03+00:00

How is Alzheimer’s diagnosed?

There are several warning signs of Alzheimer’s disease including a loss of memory, behavioral change or difficulty with reasoning or verbal skills. People who have shown these signs and symptoms of Alzheimer’s should undergo a series of medical evaluations for diagnostic purposes. Just because a person is suffering from memory loss, it doesn’t necessarily mean [...]

How is Alzheimer’s diagnosed?2017-04-06T00:20:03+00:00